Moderator: Christian Maes (Leuven)
Bernard Derrida (ENS, Paris): Statistical properties of genealogical trees
One can associate to the genealogical tree of each individuals
the distribution of repetitions of his ancestors, at a number
g of generations in the past.
By solving a simple model of a population of constant size N
with random mating,
one can show that this distribution of repetitions
reaches a stationnary shape, with a non trivial power law which
can be calculated analytically.
By comparing the genealogical trees of two distinct individuals, one
can also show that the two trees become identical within a number
log N of generations.
Paulien Hogeweg (Bioinformatics, Utrecht): Evolution of Morphogenesis
Biotic systems are preeminently multilevel systems in
which processes ad different space and time scales interact,
Moreover this property seems in many cases to be essential
for the behavior.
In this talk I will introduce a modeling approach aimed
at exploring and exploiting the multilevel nature of biotic systems,
in the context of studying morphogenesis.
We use the 2 scale CA-like CPM model to represent cells and their adhesion,
and extend this representation on the one
hand with differential gene regulation, and on the other
hand with evolution.
This way we can identify 'generic' morphogenetic mechanisms
and their coupling to cell differentiation, cell growth and division
and cell death.
Moreover we study the evolutionary dynamics which occurs under
this highly non-linear genotype-phenotype mapping.
Antal Jarai (CWI, Amsterdam): Thermodynamic limit of the Abelian sandpile model in Z^d
The Abelian sandpile model (ASM) was introduced by Bak, Tang and
Wiesenfeld as a model exhibiting so called self-organised
critical behaviour. Roughly speaking, self-organised criticality
arises when a stochastic dynamics drives a system towards a state
that is characterised by power laws. The mathematical study of
the ASM, initiated by Dhar, has revealed a rich structure, making
the analysis of the ASM more tractable than other models, and
mathematically interesting in itself. By a deep observation of
Dhar and Majumdar, the ASM can be mapped onto the uniform spanning
tree, that, at least heuristically, explains the appearance of power
laws.
In this talk I will describe the correspondence between the ASM
and spanning trees, and discuss the existence of the infinite
volume limit for the stationary measure of the model. This is
joint work with S. R. Athreya. I will also mention ongoing
research joint with F. Redig, which concerns the construction of
dynamics in the infinite volume.
Vadim Malyshev (INRIA, Rocquencourt): Stochastic chemical kinetics: history and new problems
There are N_j molecules of types j=1,...,J and a list of possible reactions. Each molecule has extra degree of freedom: the energy. Collisions are assumed to have some rates (thus defining continuous time Markov chain) and the energies of the products are defined by some probability kernel. In some cases invariant measures for this process can be found for finite N_j and for the limiting Boltzman equation. Relations with nonequilibrium chemical thermodynamics are given as well.
Ronald Meester (Vrije Universiteit, Amsterdam): A mathematical analysis of the Bak-Sneppen model for evolution
The Bak-Sneppen model has been proposed as a simple model for evolution and is supposed to exhibit self-organised critical behaviour. I will introduce the model, explain the terms and discuss some rigorous mathematical results, which come close to proving some conjectures by phycisists. In particular, I will discuss the limit of the stationary distribution as the system size tends to infinity.
Jacek Miekisz (Wydzial Matematyki, Warszawa): Long-run behavior in stochastic evolutionary games
Socio-economic systems can be viewed as systems of many interacting
agents or players. We will explore similarities and differences between
systems of many interacting players maximizing their individual payoffs
and particles minimizing their interaction energy. In particular, we will
compare the notion of a Nash equilibrium in game theory with that
of a ground state in classical lattice-gas models.i
We will study the long-time behavior of a discrete-time dynamics
in spatial games in which players adapt to their neighbors by choosing
with a high probability the strategy which maximizes the sum of the payoffs
obtained from individual games and with a small probability, representing
the noise of the system, they make mistakes.
We will investigate such stochastic dynamics in the limits of an infinite
number of players and zero noise and present
examples where the order of taking these limits is essential.
Livio Triolo (Dipartimento di Matematica, Roma): Space structures and different scales for many-component biosystems
The right scale of description, and more generally, the matching between
different scales, in modelling physical or biological systems, presents a
substantial interest and related difficulties.
This applies for instance to competition/diffusion models of different
species, or to the invasion process by an aggressive population against
a native one, like tumor cells in a normal tissue.
The main point in these investigations is to understand the fate
of the system in the long run.
It may be possible that under some circumstances
the evolution strongly depends on the space structures: a space homogeneous
situation behaves in a very different way than a space-patterned one.
Moreover if singularities, like cusps or filaments, are macroscopically present,
a local matching asymptotics may be needed to reveal their structure.
At more fundamental level, in the evolution of a many-component system
like the ones introduced above, clusters may form: this can be considered as a
strategy of survival as the evolution runs at very different pace, providing
a bridge between different regimes.
Some concrete examples from biomathematical modelling will be given.